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Petsmile VS The Regular Pet Toothpaste Brand

VOHC Accepted, Clinically Proven Results

The Veterinary Oral Health Council (VOHC) was founded in 1997 in order to provide an objective means to recognize efficacious products. A panel including veterinary dentists, dental scientists and  various organizations created a system of product review and acceptance for pet dental products. Products undergo extensive tests, with two separate trials required to statistically validate the results. During these trials, Petsmile showed a 62% greater reduction in plaque and a 28% greater reduction in gingivitis than the control pet toothpaste. Petsmile became the first toothpaste awarded the VOHC Acceptance Seal for plaque inhibition. The VOHC Acceptance Seal is recognized worldwide.

Proprietary Brush-Free Calprox® Formula

Petsmile is powered by our proprietary ingredient: Calprox®, which is an encapsulated form of Calcium Peroxide and minerals. Calprox® works by gently dissolving the protein pellicle, a bio-film that forms on your pet’s teeth, and remineralizes enamel. Bacteria, plaque and stains adhere to this bio-film; if the protein pellicle is left on your pet’s teeth, it can lead to tooth decay and periodontal disease. Using Petsmile once or twice daily will significantly improve your pet’s oral health by inhibiting plaque and tartar buildup, while whitening teeth. All you need to do is apply Petsmile Toothpaste onto your cat or dog’s teeth. Your pet’s tongue will naturally do the rest. You can use your finger or our Applicator Swabs, but for best results, we recommend using our Professional Pet Toothbrush.

Human Quality Ingredients

Petsmile uses only human-grade ingredients, meaning that Petsmile Toothpaste is so safe that you could use it too. Petsmile contains calcium, magnesium, phosphates, to remineralize enamel.

BPA-Free Packaging

Bisphenol A, also known as BPA, is a chemical primarily used in the production of polycarbonate plastics. In other words, BPA is present in many plastic items, such as tupperware, water bottles, food containers, toothpaste tubes, etc. According to the National Institute of Environmental Health Sciences (NIEHS), some animal studies report adverse effects to fetuses and newborn animals exposed to BPA. Petsmile is completely BPA-Free.


Parabens are a group of chemicals that are used as preservatives in cosmetic products in order to prevent bacteria and mold growth. Research indicates that parabens have endocrine-disrupting compounds, and can potentially interfere with hormones and consequently can have negative effects on developmental, reproductive and neurological systems, according to American Chemical Society. Petsmile contains absolutely no Parabens.

Sulfate-Free (No SLS or SLES)

Sodium Lauryl Sulfate (SLS) and Sodium Lauryl Ether Sulfate (SLES) are chemicals commonly found in a variety of grooming products, hair care products, dental care products, bath products, and cleaning products. SLS and SLES are responsible for creating the “foaming” effect of many of these products. According to the most recent safety assessment of SLS, conducted in 1983, SLS is not harmful if used briefly and then rinsed from human skin. However, when it comes to pets, SLS is found to irritate the skin when applied topically (in shampoo, for example), and can cause gastrointestinal problems when ingested. Petsmile is completely Sulfate-Free.


Crystalline Silica is a common mineral, which comprises many familiar materials, including sand, stone and concrete. Silica is found in many toothpastes in the form of Hydrated Silica. Hydrated Silica is extremely abrasive, and can damage tooth enamel leading to tooth sensitivity. The function of this high abrasivity is to scrape away plaque and bacteria, but at the cost of damaging tooth enamel. Since tooth enamel does not grow back, it is essential to minimize abrasivity on your pets teeth (and yours too)! Petsmile toothpaste is completely Silica-Free.

Allergen Free

Petsmile is free of all known allergens. Petsmile contains absolutely no gluten, soy, wheat, or corn. Petsmile is vegan, containing no protein, dairy, or animal by-products.

Made in America

All of Petsmile’s ingredients are sourced in the United States, and Petsmile Toothpaste is manufactured in the United States.

Convenient Subscription Program

For just $20 every 4 months (that’s only 14 cents per day), get Petsmile’s Dental System automatically shipped, hassle free.  The dental system includes Petsmile London Broil Pet Toothpaste 2.5oz and our patented Dual End Toothbrush. You can manage your subscription by logging in to your account on our website. For more information, feel free to reach out to us by emailing


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